STONE (Study of Tamsulosin for Urolithiasis in the Emergency Room) was a multi-center randomized clinical trial sponsored by The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The primary objective of this study was to determine the effect of tamsulosin on patients with a kidney stone within 28 days.

The study was conducted from 2008 to 2017.  Links to the published results appear below.

• Effect of Tamsulosin on Passage of Symptomatic Ureteral Stones: A Randomized Clinical Trial
  DOI: 10.1001/jamainternmed.2018.2259  PMCID: PMC6082698
• Design and challenges of a randomized clinical trial of medical expulsive therapy (tamsulosin) for urolithiasis in the emergency department
  DOI: 10.1016/j.cct.2016.11.010  PMCID: PMC5167651
• Analgesic and Opioid Use for Patients Discharged from the Emergency Department with Ureteral Stones
  DOI: 10.1089/end.2020.0835  PMCID: PMC8336240

Clinicaltrials.gov:  NCT00382265